Treatment continuation in patients receiving biological agents or conventional DMARD therapy

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Treatment continuation in patients receiving biological agents or conventional DMARD therapy.

OBJECTIVE To compare drug continuation rates in patients with rheumatoid arthritis who start on a biological agent and in a control group of patients with a change in disease modifying antirheumatic drug (DMARD) treatment after previous DMARD failure. METHODS Patients with rheumatoid arthritis enrolled in the German biologics register between May 2001 and September 2003 were included in the s...

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EXTENDED REPORT Treatment continuation in patients receiving biological agents or conventional DMARD therapy

A Zink, J Listing, S Kary, P Ramlau, M Stoyanova-Scholz, K Babinsky, U von Hinueber, E Gromnica-Ihle, S Wassenberg, C Antoni, P Herzer, J Kekow, M Schneider, R Rau . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....

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Treatment Continuation in Patients Receiving Biologics or Conventional DMARD Therapy

Objective: To compare drug survival rates in patients with rheumatoid arthritis (RA) who start on a biologic agent to a control group of patients with a change in DMARD therapy after previous DMARD failure. Patients and Methods: Patients with RA enrolled in the German biologics register between May 2001 and September 2003 were included in the study. Data were available for 511 patients treated ...

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Tuberculosis screening in patients receiving biological therapy.

AIM Biological therapies are a risk factor for tuberculosis (TB). Portuguese recommendations recommend universal baseline screening for TB before starting biologics (2006) and annually thereafter if screened negative (2012 update). The gain with re-screening remains unknown. We aimed to i)identify the risk of latent TB infection at baseline screening among patients candidates to initiate biolog...

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Small Molecule DMARD Therapy and Its Position in RA Treatment

Small molecule disease-modifying antirheumatic drugs (DMARDs) played a central role in drug therapy for rheumatoid arthritis (RA) before biological preparations (biologics) came into extensive use for the treatment of this disease. Unlike non-steroidal anti-inflammatory drugs (NSAIDs) and steroids, which primarily alleviate the symptoms of RA such as pain and inflammation, DMARDs are known to s...

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 2005

ISSN: 0003-4967

DOI: 10.1136/ard.2004.031476